Advanced Diagnostics & Therapeutics is a community of affiliated researchers who tackle a wide range of biomedical and environmental health problems - such as sepsis, cancer, influenza, wound healing, drug addiction, mosquito-borne diseases, autism, cystic fibrosis, air pollution, invasive species,and many others - through innovation, invention, and real-world applications.

This work is accomplished through a broad network of academic, corporate, and clinical partners, including the IU-School of Medicine, Naval Medical Research Center, Saint Joseph Health System/Trinity Health, Memorial Hospital/Beacon Health, Marshfield Clinic, Wertheim College of Medicine at Florida International University, American Diabetes Association, and Feinstein Institute for Medical Research/Northwell Health.

In 2015, over $77 million in new proposals were affiliated with AD&T and affiliated grant awards grew by 9%, to a total of $6.6 million. These included awards from the Defense Advanced Research Projects Agency, National Science Foundation, National Institutes of Health, and companies like MedImmune and Snowy Range Instruments.

AD&T supported technologies are being commercialized by start-ups such as Enlightened Diagnostics, Contect, Hsiri Diagnostics, NanDio, and the winner of the most recent McCloskey Business Plan Competition, Certus Therapeutics.

The initiative provides a number of funded research opportunities for students, including the Berry Family Foundation Graduate Fellowships, the Leiva Graduate Fellowship in Precision Medicine, and the new Precision Medicine Research Fellowships at the Feinstein Institute.

Advanced Diagnostics & Therapeutics is a part of Notre Dame Research.